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Allergy Articles & Updates

fish allergy

12/15/2021

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Fish Allergy
Fish allergens
Although 𝐟𝐢𝐬𝐡 𝐚𝐥𝐥𝐞𝐫𝐠𝐲 is common, fortunately, it is not as common as other allergies.⁣

Its incidence varies from country to country, and around 40% of people with fish allergy had their first reaction when they were adults.⁣

In 𝘌𝘶𝘳𝘰𝘱𝘦, less than 0.1% of children have a fish allergy.⁣


  • The protein causing most of the allergic reactions is called 𝐏𝐚𝐫𝐯𝐚𝐥𝐛𝐮𝐦𝐢𝐧, and it exists in the fish’s muscle.⁣
  • Some species will have other allergens, which might also lead to allergic reactions.⁣

















𝐂𝐨𝐝 has been the primary source of studies and information regarding fish allergy.⁣

Though most fishes contain this protein, this 𝐃𝐎𝐄𝐒 𝐍𝐎𝐓 mean that an allergy to a fish will lead to an allergy to all fish.⁣
  • Expect to have cross-reactions between fish in the same family (see the tables I made) but to a lesser extent between fish from different groups.⁣
  • Studies show that, in this case, the cross-reactivity is moderate or small.⁣

If there were no specific allergens on the table I made, it is because none has been identified yet, though some proteins have been.⁣

Some main aspects to note are the following:⁣
  1. 𝐄𝐞𝐥 and 𝐜𝐨𝐝 likely cross-react⁣
  2. 𝐀𝐧𝐜𝐡𝐨𝐯𝐲 and 𝐜𝐨𝐝 cross-sensitivity is found in nearly 35% of children⁣
  3. 𝐀𝐧𝐜𝐡𝐨𝐯𝐲 has a high content of 𝘩𝘪𝘴𝘵𝘢𝘮𝘪𝘯𝘦, so some reactions might not be allergic⁣
  4. 𝐅𝐢𝐬𝐡 𝐠𝐞𝐥𝐚𝐭𝐢𝐧𝐞 is used in medication, like in 𝘷𝘢𝘤𝘤𝘪𝘯𝘦𝘴, but generally do not lead to a reaction in people who are allergic to fish⁣
  5. Fish allergies typically are 𝐥𝐢𝐟𝐞𝐥𝐨𝐧𝐠⁣

There are cases in which an apparent allergic reaction to fish has normal investigations.⁣
  • In some cases, this might be due to the presence of a parasite called 𝐀𝐧𝐢𝐬𝐚𝐤𝐢𝐬.⁣
  • Investigation for this parasite should be done through blood tests.⁣

Final note:⁣
Think of the fish in a 𝘧𝘪𝘴𝘩 𝘵𝘢𝘯𝘬!


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Frog legs allergy
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    Dr Costa is a Consultant Paediatrician and fellow of the Royal College of Paediatrics and Child Health.

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