It was first described more than 60 years ago but only recently started to be more noted and looked into.⁣

In 2011 the 𝘌𝘶𝘳𝘰𝘱𝘦𝘢𝘯 𝘍𝘰𝘰𝘥 𝘚𝘢𝘧𝘦𝘵𝘺 𝘈𝘨𝘦𝘯𝘤𝘺 raised concerns regarding the high levels of amines (histamine included) present in foods bought in supermarkets, which might be considered a health risk.⁣

• It affects around 1% of the population, with nearly 80% of those being of middle age.⁣
• It happens when there is an imbalance between the amount of histamine circulating and our capacity to degrade it.⁣

Symptoms can happen due to either deficiency of the enzymes that degrade histamine or medication, leading to decreased enzymatic activity.⁣

The main symptoms depend on the organs affected⁣

• When the problem is 𝐃𝐀𝐎 deficiency⁣

1. Headaches⁣
2. Nausea and vomiting⁣
3. Diarrhoea, abdominal pain and problems with digestion⁣
4. Blocked nose⁣
5. Sneezing⁣
6. Itchy skin, rashes, and hives⁣
7. Asthma and difficulty breathing⁣
8. Hypotension⁣
9. Irregular heartbeat⁣
10. Muscular and joint pains⁣

• When the problem is 𝐇𝐍𝐌𝐓 deficiency, mainly it affects⁣

1. Brain⁣
2. Liver⁣
3. Lining of lungs⁣

The best way to reduce symptoms is by either reducing or stopping eating foods containing histamine or taking antihistamines.⁣

The use of DAO (Diamine Oxidase) supplements is still debatable.

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