A common source of debate, misconception and confusion is “๐ค๐ข๐ฏ ๐ฎ๐บ ๐ค๐ฉ๐ช๐ญ๐ฅ ๐ฃ๐ฆย ๐ท๐ข๐ค๐ค๐ช๐ฏ๐ข๐ต๐ฆ๐ฅย ๐ช๐ง ๐ฉ๐ฆ/๐ด๐ฉ๐ฆ ๐ฉ๐ข๐ด ๐ข๐ฏย ๐ฆ๐จ๐จ ๐ข๐ญ๐ญ๐ฆ๐ณ๐จ๐บ?”.โฃ
Especially now with the circulatingย Pfizerย andย AstraZenecaย (Oxford)ย COVID19 vaccines, many have asked me about their safety.
But let’s start with the basics.
๐๐จ ๐ฐ๐ก๐ฒ ๐ข๐ฌ ๐ข๐ญ ๐ญ๐ก๐๐ญ ๐ฆ๐จ๐ฌ๐ญ ๐จ๐ ๐ญ๐ก๐๐ฆ ๐ฎ๐ฌ๐ ๐ก๐๐ง๐ฌ’ ๐๐ ๐ ๐ฌ?โฃ
The process of growing a virus in an egg leads to that virus becoming less infectious to the human being, but still leading to a protective effect against potential infections in the future.โฃ
After a virus is injected, the egg will be sealed with gelatine. This is normally made from pork protein.
On the process of collecting the grown virus from the egg, a small amount of protein will come along as well. This can potentially lead to an allergic reaction.
๐๐๐โฃ
Saying this, other components might lead to allergic reactions.โฃ
๐๐ฉ๐ฆ ๐NIFFLE ๐ด๐ต๐ถ๐ฅ๐ช๐ฆ๐ด have shown the safety of the Nasal Flu vaccine.โฃ
Several studies have shown that the LAIV (Live Attenuated Influenza Vaccine) that contain less than 0.12ฮผg/mL (so 0.06 ฮผg for a 0.5 mL dose) is safe for patients with an egg allergy.โฃ
๐๐๐๐ข๐๐ฌโฃ
To produce this vaccine, the virus is grown on chick embryonic fibroblast cells.
In case a patient with an egg allergy needs this vaccine, there two other options that can be used, as they do not contain egg:โฃ
๐๐๐ฅ๐ฅ๐จ๐ฐ ๐๐๐ฏ๐๐ซ ๐ฏ๐๐๐๐ข๐ง๐โฃ
๐๐ฆ๐ฉ๐จ๐ซ๐ญ๐๐ง๐ญ:โฃ
Finally, the COVID19 vaccines:
This means both vaccines are safe to be used in egg-allergic children.
The only children who need to be vaccinated in a hospital are those with an allergy to eggs, with previous anaphylaxis to egg or who had a cardiorespiratory reaction needing admission to Intensive Care or those with coexisting active, chronic asthma.โฃ
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